SODIUM BICARBONATE SYMPORTERS Meaning and
Definition
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Sodium bicarbonate symporters are a group of integral membrane proteins that facilitate the transport of sodium ions and bicarbonate ions across cell membranes in a coupled manner. They belong to the family of secondary active transporters, also known as symporters, because they simultaneously transport two different molecules in the same direction across the membrane.
The primary function of sodium bicarbonate symporters is to maintain the balance of pH and electrolyte concentrations in the body. They are predominantly found in various tissues and organs, including the kidneys, intestines, pancreas, and lungs, where they play crucial roles in acid-base regulation and maintaining proper cellular pH.
These symporters typically work by utilizing the energy derived from the electrochemical gradient of sodium ions across the cell membrane. They actively transport sodium ions from areas of low concentration to areas of high concentration, while simultaneously moving bicarbonate ions in the same direction. This process is essential for the reabsorption of bicarbonate ions and the excretion of waste products, ultimately contributing to the maintenance of systemic pH.
Malfunctioning or mutations in sodium bicarbonate symporters can lead to various health disorders, including renal tubular acidosis, cystic fibrosis, and some forms of hypertension. Thus, understanding the functioning and regulation of these symporters is imperative to comprehend the underlying mechanisms behind these diseases and potentially develop targeted therapeutic interventions.
Common Misspellings for SODIUM BICARBONATE SYMPORTERS
- aodium bicarbonate symporters
- zodium bicarbonate symporters
- xodium bicarbonate symporters
- dodium bicarbonate symporters
- eodium bicarbonate symporters
- wodium bicarbonate symporters
- sidium bicarbonate symporters
- skdium bicarbonate symporters
- sldium bicarbonate symporters
- spdium bicarbonate symporters
- s0dium bicarbonate symporters
- s9dium bicarbonate symporters
- sosium bicarbonate symporters
- soxium bicarbonate symporters
- socium bicarbonate symporters
- sofium bicarbonate symporters
- sorium bicarbonate symporters
- soeium bicarbonate symporters
- soduum bicarbonate symporters
- sodjum bicarbonate symporters
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