PUROMYCIN Meaning and
Definition
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Puromycin is a naturally occurring antibiotic with potential biomedical applications. It is classified as an aminonucleoside compound and belongs to the class of drugs known as translation inhibitors. Puromycin works by inhibiting protein synthesis in both prokaryotic and eukaryotic cells. It accomplishes this by mimicking the structure of the aminoacyl-tRNA molecule, causing premature chain termination during protein synthesis.
In prokaryotic cells, puromycin inserts itself into the nascent peptide chain, leading to early termination of translation and the release of truncated proteins. In eukaryotic cells, puromycin incorporates itself into the growing peptide chain, resulting in peptidyl-puromycin formation, which is released from the ribosome and inhibits further protein synthesis.
Due to its ability to disrupt protein synthesis, puromycin has been widely used in research laboratories as a tool to study gene expression, protein synthesis, and ribosome function. It is commonly employed to generate protein knockouts or to study translation events. Puromycin resistance can also be utilized in molecular biology techniques to select for cells that have been successfully transfected with specific genes.
While puromycin is primarily used in research settings, it has also been investigated for potential therapeutic applications. Research suggests that it can be useful in the treatment of certain types of cancer, as it has shown cytotoxic effects on tumor cells by inducing apoptosis and inhibiting cell growth. Further studies are needed to determine its efficacy and safety profile in clinical settings.
Common Misspellings for PUROMYCIN
Etymology of PUROMYCIN
The word "Puromycin" is derived from the combination of two parts. The first part, "Puro", is derived from "purine", which is a type of organic compound. The second part, "Mycin", is derived from "Mycobacterium", which is a genus of bacteria known for antibiotic production. Therefore, the etymology of "Puromycin" signifies its origin as a compound derived from purine and produced by the bacteria Mycobacterium.
Similar spelling words for PUROMYCIN
- Paramyosin,
- parmesan,
- paramucin,
- Beromycin,
- preomission,
- bremzen,
- promession,
- bromeosin,
- bromosin,
- brahmsian,
- bramson,
- promocion,
- boromycin,
- Bryamycin,
- permission,
- perry mason,
- promicin,
- Promazine,
- brimson.
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