Primary choroid plexus neoplasms are a type of tumor that mainly develop within the choroid plexus structures of the brain. The choroid plexus is responsible for producing cerebrospinal fluid (CSF), which fills and nourishes the ventricles of the brain. These tumors arise from the abnormal growth of cells within the choroid plexus tissues and can be either benign (non-cancerous) or malignant (cancerous).
The primary choroid plexus neoplasms often occur in children and are relatively rare. They typically manifest as slow-growing masses within the ventricles or surrounding areas of the brain. These tumors can obstruct the normal flow of CSF, leading to an accumulation and increased pressure in the brain, causing symptoms like headaches, nausea, seizures, and changes in mental status.
Histologically, primary choroid plexus neoplasms can be further categorized into different types, including choroid plexus papilloma (benign) and choroid plexus carcinoma (malignant). Papillomas are usually localized and well-differentiated, while carcinomas tend to be more invasive and aggressive.
Diagnosis of primary choroid plexus neoplasms typically involves neuroimaging techniques like MRI or CT scans to visualize the tumor and determine its characteristics. Surgical resection, if feasible, is the primary treatment option, aiming to remove as much of the tumor as possible. In some cases, adjuvant therapies such as radiation therapy or chemotherapy may be employed to target any remaining cancer cells or to treat cases where complete surgical removal is not achievable.
Follow-up care and monitoring are crucial for individuals with primary choroid plexus neoplasms, as there is a risk
