MACROLIDE ANTIBIOTICS Meaning and
Definition
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Macrolide antibiotics are a class of antibiotics characterized by a large ring-shaped structure called a macrolactone. They are derived from Streptomyces bacteria and are primarily used to treat bacterial infections. These antibiotics work by inhibiting bacterial protein synthesis, specifically targeting the 50S ribosomal subunit responsible for protein synthesis within the bacteria.
Macrolide antibiotics have a broad spectrum of activity, meaning they have the ability to fight against a wide range of bacterial species. They are particularly effective against gram-positive bacteria, such as Streptococcus and Staphylococcus, but can also be effective against some gram-negative bacteria, including Haemophilus influenzae and Moraxella catarrhalis.
Macrolide antibiotics are well-known for their ability to penetrate into various tissues and bodily fluids, including the respiratory tract, skin, and soft tissues. This makes them ideal for treating infections in these areas. They are commonly prescribed to treat respiratory tract infections, such as pneumonia, bronchitis, and sinusitis. They are also used to treat skin and soft tissue infections, such as cellulitis and impetigo.
These antibiotics are generally well-tolerated and have a relatively low toxicity profile. However, they can sometimes cause gastrointestinal side effects, such as nausea, vomiting, and diarrhea. They may also occasionally cause liver abnormalities or allergic reactions in some individuals.
Overall, macrolide antibiotics are an important class of antibiotics that play a crucial role in the treatment of bacterial infections, providing a viable treatment option for a variety of different conditions.
Common Misspellings for MACROLIDE ANTIBIOTICS
- nacrolide antibiotics
- kacrolide antibiotics
- jacrolide antibiotics
- mzcrolide antibiotics
- mscrolide antibiotics
- mwcrolide antibiotics
- mqcrolide antibiotics
- maxrolide antibiotics
- mavrolide antibiotics
- mafrolide antibiotics
- madrolide antibiotics
- maceolide antibiotics
- macdolide antibiotics
- macfolide antibiotics
- mactolide antibiotics
- mac5olide antibiotics
- mac4olide antibiotics
- macrilide antibiotics
- macrklide antibiotics
- macrllide antibiotics
Etymology of MACROLIDE ANTIBIOTICS
The word "macrolide" is derived from the Greek words "makrós", meaning "large" or "long", and "eidos", meaning "form" or "shape". This refers to the large lactone ring structure found in macrolide antibiotics.
The term "antibiotic" stems from the combination of two root words: "anti", which means "against", and "bios", meaning "life". It was coined by the microbiologist Selman Waksman in 1942 to describe any substance produced by a microorganism that inhibits the growth of other microorganisms.
Therefore, "macrolide antibiotics" refers to a class of antibiotics that possess a large lactone ring structure and are effective against various microorganisms, inhibiting their growth or causing their death.
