DCC GENES Meaning and
Definition
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DCC genes, also known as Deleted in Colorectal Cancer genes, are a group of genes that have been extensively studied in the context of colorectal cancer development and progression. The term "deleted" in the name refers to their loss of function in certain cases of colorectal cancer.
DCC genes are responsible for encoding a transmembrane receptor protein called "Deleted in Colorectal Cancer" or DCC protein. This protein plays a crucial role in normal cell growth, differentiation, and the maintenance of tissue structure. It is particularly crucial during embryonic development, acting as a guidance receptor for the growing nerve cells to ensure proper neural circuitry formation.
In colorectal cancer, alterations in DCC genes such as deletions, mutations, or epigenetic changes can lead to the loss of DCC protein function. This loss impairs the normal growth control mechanisms, making cells more prone to uncontrolled division and tumor formation in the colon and rectum.
Researchers have identified several tumor-suppressive functions associated with DCC genes, including the regulation of cellular growth, inhibition of angiogenesis (formation of new blood vessels), and prevention of metastasis (spread of cancer to other organs). Therefore, abnormal DCC gene activity can contribute to the progression of colorectal cancer.
The study of DCC genes and their expression patterns has provided valuable insights into the molecular mechanisms underlying colorectal cancer development. This knowledge has the potential to aid in early diagnosis, prognosis, and the development of targeted therapies for colorectal cancer patients.
Common Misspellings for DCC GENES
- scc genes
- xcc genes
- fcc genes
- rcc genes
- ecc genes
- dxc genes
- dvc genes
- dfc genes
- dcx genes
- dcv genes
- dcf genes
- dcd genes
- dcc fenes
- dcc venes
- dcc benes
- dcc henes
- dcc yenes
- dcc tenes
- dcc gwnes
- dcc gsnes
Etymology of DCC GENES
The acronym DCC stands for Deleted in Colorectal Cancer. The term DCC Genes refers to a specific set of genes known as the Deleted in Colorectal Cancer genes. The etymology of the acronym itself originates from its discovery in the field of cancer research. The genes were identified as being commonly deleted or mutated in colorectal cancer cells, and hence, they were named Deleted in Colorectal Cancer genes.
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