CBFBP Meaning and
Definition
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CBFBP is an acronym that stands for "Core Binding Factor Beta Subunit, Polyglutamine Repeat Protein," and it refers to a specific protein involved in genetic regulation. This protein is encoded by the CBFB gene and plays a crucial role in the formation of a transcriptional regulator complex known as core-binding factor (CBF). The CBF complex, consisting of two subunits CBFA2 and CBFB, is responsible for binding to specific DNA sequences and either activating or repressing the transcription of target genes.
CBFBP is particularly distinguished by the presence of polyglutamine repeat within its structure. Polyglutamine repeats are stretches of amino acids where glutamine residues are repeated multiple times. The number of repeats in CBFBP may vary among individuals due to genetic variations, resulting in different lengths of the polyglutamine tract.
Research suggests that CBFBP and other proteins with polyglutamine repeats may be involved in various cellular processes, including gene regulation, protein-protein interactions, and DNA repair. These proteins often display the characteristics of intrinsically disordered proteins, lacking a well-defined three-dimensional structure.
The precise role of CBFBP and its polyglutamine repeat in cellular function and disease development is still an active area of investigation. Abnormalities in the CBFBP gene or alterations in the polyglutamine tract have been associated with certain diseases, including some cancers and neurodegenerative disorders. Further research is necessary to fully understand the functional significance and implications of CBFBP in various biological contexts and its potential as a therapeutic target.
Common Misspellings for CBFBP
- xbfbp
- vbfbp
- fbfbp
- dbfbp
- cvfbp
- cnfbp
- chfbp
- cgfbp
- cbvbp
- cbtbp
- cbfvp
- cbfnp
- cbfhp
- cbfbo
- cbfbl
- cbfb0
- xcbfbp
- cxbfbp
- vcbfbp
- cvbfbp
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